Disposition Index Calculator

What is the Disposition Index?

The Disposition Index is a powerful concept in metabolic health that assesses whether the pancreatic beta-cells are producing enough insulin to compensate for an individual's level of insulin sensitivity.

A healthy pancreas should increase insulin secretion to overcome resistance. The Disposition Index quantifies this relationship, typically by multiplying a measure of beta-cell function (like HOMA-BETA) by a measure of insulin sensitivity (like QUICKI).

Why is it a Powerful Marker?

• It provides a more complete metabolic picture than either insulin sensitivity or secretion alone.
• A low Disposition Index is a strong predictor of future risk for developing Type 2 Diabetes.
• It helps understand the pathophysiology of hyperglycemia: is it due to poor insulin production, poor insulin action, or both?

Interpreting Your Result (Reference Guide)

Holistic Metabolic Health

Improving your Disposition Index involves a dual approach: enhancing insulin sensitivity and supporting pancreatic beta-cell health.

• Follow a nutrient-dense, balanced diet.
• Engage in consistent physical activity.
• Maintain a healthy body weight.
• Prioritize adequate sleep and manage stress.
• Avoid smoking and excessive alcohol consumption.