Creatinine Clearance Cockcroft-Gault Formula
Estimate kidney function instantly using the Cockcroft-Gault formula
Last updated on: December 20, 2025
Creatinine Clearance (CrCl) Calculator
How This Creatinine Clearance Calculator Works
This creatinine clearance calculator uses the Cockcroft-Gault equation to estimate your glomerular filtration rate (GFR) from your serum creatinine level. It is the standard method for assessing kidney function before adjusting medication doses.
While a creatinine clearance test can be done with 24-hour urine collection, this calculator provides an instant estimate that is sufficient for most clinical purposes.
Why Calculate Creatinine Clearance?
- **Medication Safety**: This creatinine clearance calculation is essential for correct dosing of antibiotics, diabetes drugs, and pain medications.
- **Kidney Disease Detection**: Regular creatinine clearance testing helps identify early kidney damage.
- **Treatment Monitoring**: Track how kidney function changes over time with this calculator.
Understanding Your Creatinine Clearance Result
Normal Kidney Function (≥ 90 mL/min):
Your creatinine clearance is within normal range. Continue regular health maintenance.
Mild Reduction (60-89 mL/min):
Mild decrease in kidney function. Monitor blood pressure and avoid nephrotoxic substances.
Moderate Reduction (45-59 mL/min):
Moderate kidney impairment. Consult a doctor for further evaluation.
Moderate to Severe Reduction (30-44 mL/min):
Significant kidney impairment. Requires medical management.
Severe Reduction (15-29 mL/min):
Severe kidney damage. Nephrology consultation recommended.
Kidney Failure (< 15 mL/min):
End-stage renal disease. Requires dialysis or transplant evaluation.
Maintaining Healthy Kidney Function
Your creatinine clearance result reflects current kidney function. To protect your kidneys long-term:
- Monitor Blood Pressure: Keep below 130/80 mmHg to reduce kidney strain.
- Control Blood Sugar: Maintain HbA1c below 7% if diabetic.
- Stay Hydrated: Drink adequate water based on your activity level.
- Avoid NSAIDs: Limit use of ibuprofen and similar pain relievers.
- Healthy Diet: Reduce salt, processed foods, and maintain healthy weight.
- Regular Testing: Annual creatinine clearance check if at risk.
- Quit Smoking: Smoking accelerates kidney damage.
This page has been medically reviewed by Dr. Khoulah Attia – PharmD, Immunology Specialist.