H. pylori Pre-Test Probability
Estimate likelihood of infection before testing.
Last updated on: September 15, 2025
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What is Pre-Test Probability?
Pre-test probability estimates the likelihood of H. pylori infection before ordering diagnostic tests.
It helps clinicians decide whether to test or treat, considering patient risk factors and regional prevalence.
Why Use This Tool?
- Reduce unnecessary testing in low-risk patients.
- Identify patients who need further evaluation.
- Adapt decisions based on regional prevalence.
Diagnostic Guidance
- Low probability: usually no testing required.
- Moderate probability: recommend non-invasive tests (urea breath test, stool antigen).
- High probability: endoscopy or empiric treatment may be appropriate.
Treatment Advice
- Triple or quadruple therapy depending on resistance patterns.
- Confirm eradication with a follow-up test after 4–6 weeks.
- Avoid unnecessary antibiotics in low-risk cases.
Clinical Notes
Prevalence varies widely across regions. Consider local guidelines and family history.
This page has been medically reviewed by Dr. Khoulah Attia – PharmD, Immunology Specialist.