Non-HDL Cholesterol Calculator
A comprehensive measure of atherogenic cholesterol
Last updated on: July 1, 2025
Non-HDL-C Calculation
What is Non-HDL Cholesterol?
Non-HDL Cholesterol (Non-HDL-C) is a simple yet powerful measure of cardiovascular risk. It is calculated by subtracting your High-Density Lipoprotein (HDL, or "good") cholesterol from your Total Cholesterol.
The resulting value represents the total amount of "bad," atherogenic (plaque-forming) cholesterol in your blood, including LDL, VLDL, IDL, and Lp(a).
Why is Non-HDL-C Important?
- It is a better predictor of cardiovascular risk than LDL-C alone, especially in people with high triglycerides, diabetes, or metabolic syndrome.
- It does not require a fasting sample, making it a convenient and reliable marker.
- Many clinical guidelines now consider Non-HDL-C a primary or secondary target of therapy.
Interpreting the Result
Desirable (< 130 mg/dL or < 3.4 mmol/L):
This level is associated with a lower risk of cardiovascular disease.
Borderline High (130-159 mg/dL or 3.4-4.1 mmol/L):
This level indicates a borderline risk. Lifestyle improvements are recommended.
High (160-189 mg/dL or 4.1-4.9 mmol/L):
This level indicates a high risk for cardiovascular disease. Medical consultation is advised.
Very High (≥ 190 mg/dL or ≥ 4.9 mmol/L):
This level indicates a very high risk. Aggressive management and medical treatment are often necessary.
Managing Your Non-HDL Cholesterol
Lowering Non-HDL cholesterol is a key goal in preventing heart disease. This is achieved through lifestyle changes and, if necessary, medication.
- Follow a heart-healthy diet low in saturated and trans fats.
- Increase physical activity to improve your overall lipid profile.
- Achieve and maintain a healthy weight.
- Quit smoking, as it damages blood vessels and affects cholesterol levels.
- Your doctor may prescribe medications like statins to help lower your levels.
This page has been medically reviewed by Dr. Khoulah Attia – PharmD, Immunology Specialist.